Rituximab: The First Monoclonal Antibody Approved for Cancer Treatment

Copyright © 2023 Nudelman/ShutterstockRituximab was first approved by the FDA in 1997 for the treatment of CD20-positive B-cell non-Hodgkin’s lymphoma (NHL). Its approval marked a significant milestone in oncology and paved the way for the development of antibody-based therapies. By targeting the

Nov 18, 2024
The Evolution of Antibody-Drug Conjugates (ADCs) in Cancer Therapy

Antibody-drug conjugates (ADCs) combine the specificity of monoclonal antibodies with the potent cytotoxic effects of chemotherapeutic agents. The development of ADCs traces back over a century and mirrors advancements in molecular biology and biotechnology, resulting in several approved drugs used in oncology today.

Oct 22, 2024
The Promise of VHH Antibodies

Discover the role of VHH antibodies in diagnostics & therapeutics, from viral treatments to precision diagnostics. Learn how they revolutionize antibody-based applications.

Jun 05, 2024
Muronomab: The First Approved Monoclonal Antibody

Discover the history of Muronomab (Orthoclone OKT3), the first monoclonal antibody approved by the FDA for preventing transplant rejection & its impact on immunology.

May 16, 2024
The Emergence and Evolution of scFvs

Explore the history, development, and advancements of single-chain variable fragments (scFvs), their therapeutic applications, and their evolution in antibody engineering.

May 14, 2024
Biointron Hosted a Lunch & Learn Session: “Accelerating Antibody Development and ADCs”

Highlights from Biointron’s Lunch & Learn with MassBio: HTP antibody platforms, alpaca VHH discovery, bispecific antibodies, & ADC development advancements.

May 10, 2024
Engineered Antibody Formats: A Historical Perspective

Discover the evolution of engineered antibody formats from monoclonal to bispecific antibodies, highlighting milestones in immunotherapy and clinical applications.

May 08, 2024
A Historical Overview of VHH Antibodies

Explore an overview of VHH antibodies, from discovery to commercialization. Learn about their unique properties & applications in therapeutics, diagnostics & biotech!

May 04, 2024
Celebrating the International Day of Women and Girls in Science: 10 Inspiring Stories of Change

The International Day of Women and Girls in Science, celebrated on February 11th each year, stands as a global reminder of the critical role women and girls play in science and technology communities and industries. Established by the United Nations, this day aims to promote full and equal access to and participation in science to achieve gender equality and inspire future generations to break through barriers and contribute to scientific discovery and innovation.

Feb 15, 2024
Antibody History and Development

Discover the evolution of antibody research, from Emil von Behring's diphtheria work to hybridoma technology and modern recombinant antibody advancements.

Jan 20, 2024

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