The discovery of monoclonal antibodies (mAbs) for therapeutic and research applications has been a cornerstone of modern biotechnology. Two conventional approaches, hybridoma technology and single B cell screening, have historically driven the field, offering distinct strengths and limitations.

Discover the science behind hybridomas, their role in monoclonal antibody production, and their applications in research and medicine. Learn more today!

Antibody production technologies encompass various methods used to produce antibodies for therapeutic, diagnostic, and research purposes. The following are some of the primary technologies used in antibody production.

Hybridoma technology is a common method to produce monoclonal antibodies (mAbs) and involves the fusion of antibody-producing B lymphocytes obtained from immunized mice with immortal myeloma cell lines. This fusion gives rise to hybridoma cell lines which are cultivated to produce mAbs targeted against a specific antigen.

Explore antibody discovery technologies like phage display, yeast display, & computational tools. Learn about trends in multi-specific antibodies & AI integration.

Explore the process of custom antibody development – from antigen design & immunization to production & characterization – for precise research & clinical applications.

Explore advancements in hybridoma technology, including electrofusion and cell screening, and their critical applications in diagnostics, cancer therapies, and antibody research.

Discover hybridoma sequencing to prevent cell line loss, ensure 100% sequence accuracy, and enable recombinant expression for consistent antibody production.