Discover Biointron's expertise in producing bispecific antibodies using advanced methods like knobs-in-holes, Ig-scFv fusion, & Diabody-Fc fusion for innovative therapies.

Explore HTP recombinant antibody & VHH production for fast, scalable antibody discovery. Learn how Biointron’s high-throughput platform accelerates research & development.

Understand affinity maturation, from in vivo somatic hypermutation to in vitro optimization using Biointron’s FCMES-AM™ platform for improved antibody binding.

A major challenge associated with the use of murine monoclonal antibodies as a therapeutic is their immunogenicity causing a human anti-mouse antibody (HAMA) response. To tackle this issue, chimeric antibodies were created using genetic engineering techniques, combining human constant domains with mouse variable domains that recognized the human antigen of interest, thus preserving antibody specificity.

Discover hybridoma sequencing to prevent cell line loss, ensure 100% sequence accuracy, and enable recombinant expression for consistent antibody production.

Explore Single B Cell Screening, a high-throughput technique for isolating antigen-specific mAbs, accelerating antibody discovery & therapeutic development. Learn more!

Explore VHH library generation, from camelid immunization to screening & purification. Learn how Biointron accelerates nanobody discovery for research & therapeutics.