Large Scale Antibody Production-Biointron

Manufacturing therapeutic antibody or protein in large quantities is required for many applications, including in vitro study, in vivo animal study or pre-clinical trials. BioIntron large-scale manufacturing services offer scale-up production of recombinant antibodies/proteins from milligram to gram levels within weeks.

Our Advantages

Consistency

(all the product come from one batch, SDS-PAGE>95%, SEC-HPLC>95%, endotoxin level <0.1EU/mg)

Fast Turnaround Time

(as short as 4 weeks for gram level production)

Large Capacity

(up to hundred grams level)

Large Scale Up Production Service Detail

Service Step	Service Description	Timeline	Price（USD）	Deliverable
Gene synthesis and subcloning	▸Codon optimization and gene synthesis ▸Subcloning into an expression vector ▸Plasmid amplification and preparation	1 week	Inquiry	▸Expression plasmid contain GOI ▸Purified rAb/protein ▸CoA report
Pilot study	▸Transfection of mammalian cells ▸Small scale pilot evaluation ▸ QC analysis	1 week
Large scale production (up to 50L)	▸Maxi plasmid preparation ▸Transfection and expression ▸QC analysis	5-8 weeks	Inquiry

Service Step

Service Description

Timeline

Price（USD）

Deliverable

Gene synthesis and subcloning

▸Codon optimization and gene synthesis

▸Subcloning into an expression vector

▸Plasmid amplification and preparation

1 week

Inquiry

▸Expression plasmid contain GOI

▸Purified rAb/protein

▸CoA report

Pilot study

▸Transfection of mammalian cells

▸Small scale pilot evaluation

▸ QC analysis

1 week

Large scale production (up to 50L)

▸Maxi plasmid preparation

▸Transfection and expression

▸QC analysis

5-8 weeks

Inquiry