Large Scale Antibody Production

Large Scale Antibody Production

Manufacturing therapeutic antibody or protein in large quantities is required for many applications, including in vitro study, in vivo animal study or pre-clinical trials. BioIntron large-scale manufacturing services offer scale-up production of recombinant antibodies/proteins from milligram to gram levels within weeks.

Our Advantages

Consistency
Consistency

(all the product come from one batch, SDS-PAGE>95%, SEC-HPLC>95%, endotoxin level <0.1EU/mg)

Fast Turnaround Time
Fast Turnaround Time

(as short as 4 weeks for gram level production)

Large Capacity
Large Capacity

(up to hundred grams level) 

Large Scale Up Production Service Detail

Service StepService DescriptionTimelinePrice(USD)Deliverable

Gene synthesis and subcloning

Codon optimization and gene synthesis

Subcloning into an expression vector

Plasmid amplification and preparation

1 week

Inquiry

Expression plasmid contain GOI

Purified rAb/protein

CoA report

Pilot study

Transfection of mammalian cells

Small scale pilot evaluation

QC analysis

1 week
Large scale production (up to 50L)

Maxi plasmid preparation

Transfection and expression 

QC analysis

5-8 weeks

Inquiry