Manufacturing therapeutic antibody or protein in large quantities is required for many applications, including in vitro study, in vivo animal study or pre-clinical trials. BioIntron large-scale manufacturing services offer scale-up production of recombinant antibodies/proteins from milligram to gram levels within weeks.
(all the product come from one batch, SDS-PAGE>95%, SEC-HPLC>95%, endotoxin level <0.1EU/mg)
(as short as 4 weeks for gram level production)
(up to hundred grams level)
| Service Step | Service Description | Timeline | Price（USD） | Deliverable |
|---|---|---|---|---|
Gene synthesis and subcloning | ▸Codon optimization and gene synthesis ▸Subcloning into an expression vector ▸Plasmid amplification and preparation | 1 week | Inquiry | ▸Expression plasmid contain GOI ▸Purified rAb/protein ▸CoA report |
| Pilot study | ▸Transfection of mammalian cells ▸Small scale pilot evaluation ▸ QC analysis | 1 week | ||
| Large scale production (up to 50L) | ▸Maxi plasmid preparation ▸Transfection and expression ▸QC analysis | 5-8 weeks | Inquiry |