Commercial License for CHOK1BN-Biointron

Biointron‘s CHOK1BN cell line, licensed from ECACC, is suspension-adapted in basic CD media. The cell line can be sublicensed for commercial use, it meets the requirements for registration in both China and US.

Our Advantages

Adapted in basic CD medium and can apply to various medium

High stability and productivity (> 10 g/L)

Suitable for monoclonal antibody, bispecific antibody, factors, etc.

Adaption of CHOK1BN cell line

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Deliverables

Delivery	items
Host system	CHOK1BN cell line
Documentation	ECACC license order form, original invoice, COA, customs clearance report
	Suspension-adapted report
	Cell banking detection report (including sterility test, mycoplasma test, in vitro assay for the detection of viral contaminants, etc.)
	COA of FBS and Trpsin
Protocols	Cell culture protocol
Protocols	Cell line development protocol (including transfection, cell pool screening and cell clone screening)

Suitable for various medium with high monoclonal antibody yield

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For recombinant proteins: stability test for over 2 months

The doubling time of the cells is 22±1 hours. During the plateau period of feed batch, the cell density is 20-25*10^6 cell/ml,making it easier for scale up production.		Excellent batch difference, the titer variation is just <10%