Commercial License for CHOK1BN

Commercial License for CHOK1BN

Biointron‘s CHOK1BN cell line, licensed from ECACC, is suspension-adapted in basic CD media. The cell line can be sublicensed for commercial use, it meets the requirements for registration in both China and US.

Our Advantages

Adapted in basic CD medium and  can apply to various medium
Adapted in basic CD medium and can apply to various medium

High stability and productivity (> 10 g/L)
High stability and productivity (> 10 g/L)

Suitable for monoclonal antibody, bispecific antibody, factors, etc.
Suitable for monoclonal antibody, bispecific antibody, factors, etc.

Adaption of CHOK1BN cell line

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Deliverables

Deliveryitems
Host systemCHOK1BN cell line
Documentation

ECACC license order form, original invoice, COA, customs clearance report

Suspension-adapted report

Cell banking detection report (including sterility test, mycoplasma test, in vitro assay for the detection of viral contaminants, etc.)

COA of FBS and Trpsin

ProtocolsCell culture protocol

Cell line development protocol (including transfection, cell pool screening and cell clone screening)

Suitable for various medium with high monoclonal antibody yield

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For recombinant proteins: stability test for over 2 months

The doubling time of the cells is 22±1 hours. During the plateau period of feed batch, the cell density is 20-25*10^6 cell/ml,making it easier for scale up production.

Excellent batch difference, the titer variation is just <10%
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