Accelerate your research program with scalable, high-quality recombinant antibody expression solutions

At Biointron, we excel at providing reliable antibody production services faster and with uncompromising quality. Our advanced, high-throughput expression latforms deliver recombinant antibodies with high yield, reproducibility, and consistency—helping you meet critical milestones with confidence. Whether you need rapid small-scale or large-scale expression, or afucosylated, bispecific, and conjugated antibodies, Biointron offers the flexibility to match your needs.

Antibody Production Services

HTP Recombinant
Antibody Production

Our 2-week high-throughput recombinant antibody production is a leading gene-to-antibody workflow in the industry.

We offer the flexibility to rapidly express large quantities of antibodies at varying scales using HEK293 or CHO cells, both known for their efficiency in recombinant protein expression.

We will deliver high quality antibodies with low endotoxin levels (<1EU/mg) and high purity (>95% by SDS-PAGE).

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Bispecific Antibody
Production

Receive high-quality bispecific antibodies in 3-4 weeks.

Biointron supports the expression of all bispecific formats including but not limited to: Knobs-into-holes IgG, IgG-scFv fusion, CrossMab, Y-body, Bispecific T-cell Engagers (BiTEs), and more.

We utilize mammalian cell systems, such as CHO-K1 and HEK293 for antibody expression, ensuring high yield and quality. You will receive SDS-PAGE, SEC-HPLC, and endotoxin results along with the purified bispecific antibody and expression plasmids containing your gene of interest.

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Afucosylated Antibody
Expression
Platform

Upgrade the efficacy of your antibodies with our powerful afucosylation platform in 2-4 weeks.

Afucosylation has been shown to significantly enhance antibody-dependent cell-mediated cytotoxicity (ADCC). We use the engineered mammalian cell system CHOK1-FUT8 for afucosylated antibody expression.

Integrated with our high-throughput recombinant antibody expression capability and cell line development expertise, afucosylated antibodies can be rapidly produced to meet your research needs.

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Large scale Antibody
Production

Get gram-level antibody production in 2-4 weeks.

Mass production of proteins is frequently influenced by factors such as cost, turnaround time, and regulatory compliance, and is subject to stringent quality control and assurance measures.

To meet the growing demand for gram-scale proteins, and with over 10 years of expertise in protein production, Biointron has established a large-scale protein expression service using validated cell culture technology.

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RushMab Smal Scale
Antibody Production

Small-scale, high-quality antibodies in as little as 4-10 days.

RushMab™ packages are designed to offer cost-effective, time-saving solutions to meet small-scale rush needs in as fast as 8 days, with a sizable production capability formore than 5K samples.

Since 2012, we’ve delivered over 100,000 recombinant antibodies each year. Our team will give you the speed, quality, and scalability required to support the unique needs of program.

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ADC HTP
Antibody
Conjugation

Custom high-throughput antibody-drug conjugate (ADC) expression in 2-3 weeks.

Accelerate your preclinical research with our ADC conjugation platform which integrates seamlessly with our HTP antibody expression and engineering expertise.

We support both in-house and client-provided small-molecule drugs for conjugation and offer customizable DAR values. We support diverse antibody and protein types (including monoclonal and bispecific antibodies) with conjugation via non-canonical amino acids (ncAAs).

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Featured Blog

Antibody ABCs: What is Antibody Engineering?

Antibody engineering optimizes performance. Biointron outlines methods to enhance affinity, stability, and developability, advancing therapeutic antibody success.

Sep 16, 2024

Comparing In Vivo and In Vitro Antibody Production: A Strategic Guide

Antibody production can be in vivo or in vitro. Biointron compares these methods, highlighting efficiency, scalability, and suitability for different applications.

Sep 04, 2024

Why Choose Transgenic Mouse Models for Antibody Production?

Transgenic mouse models enable humanized antibody discovery. Biointron explains why they are essential tools for generating next-generation therapeutics.

Sep 02, 2024