Humanized antibodies with guaranteed affinity preservation in just 3-4 weeks.
Our antibody humanization service addresses the challenge of immunogenicity by employing CDR grafting onto selected human germline frameworks. Combined with limited back mutations to maintain loop conformation and antigen affinity, we deliver antibodies with reduced anti-drug antibody (ADA) risk and reliable performance. Our integrated bioinformatics and structural modeling platform ensures precise germline selection and sequence optimization, while minimizing the number of framework modifications. With a guaranteed affinity drop of no more than three-fold compared to the parental antibody, and a typical turnaround of 3–4 weeks, we provide a fast and dependable path for optimizing antibody candidates.
Our antibody discovery services also include:
