Biointron x NextGen Biomed 2026 Webinar: Accelerating Antibody Discovery

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Webinar Title: Accelerating Antibody Discovery: Integrating Microfluidics, HT Expression, and Early Developability Platform

During the NextGen Biomed 2026 conference in London, Lei Shi, PhD, Senior Vice President of Biointron, discussed Biointron's unique single B cell sorting-based antibody discovery process integrated with our high-throughput expression, validation and developability platforms.

This webinar presents an overview of next-generation antibody discovery using the AbDrop platform, an industrial-scale system designed to overcome the limitations of traditional methods such as hybridoma and phage display.

Attendees are introduced to a high-throughput workflow that enables direct recovery of native, full-length antibodies from plasma B cells. The session outlines how millions of B cells can be screened in a single day, with paired heavy and light chain sequences identified and validated within weeks, significantly accelerating discovery timelines. The webinar also covers the end-to-end process, including droplet-based screening, FRET sorting, next-generation sequencing, and automated expression systems capable of producing thousands of high-purity antibodies per batch.

A featured case study on PD-1 antibody discovery demonstrates the platform’s ability to generate diverse, high-affinity candidates with both blocking and agonistic functions, supported by in vitro and in vivo validation data.

RushData integrates early developability assessment, such as stability, expression, and non-specific binding, into the discovery phase. This enables faster, data-driven decision-making and reduces downstream risk.

Watch the recording here >>

About the Speaker

Lei Shi, PhD. is Senior Vice President of Biointron. He has more than 20 years of experience in antibody discovery. Previously, Lei worked for a number of pharmaceutical and biotech companies such as Johnson & Johnson with increasing responsibilities. He completed his postdoc research at MGH and Harvard Medical School and has an Executive Master's degree from the University of Pennsylvania.

Watch the recording here >>