Case Study: From Sequence to Antibodies in Weeks - How Macomics Worked Smarter with Biointron

When you’re a small biotech with big ambitions, every week counts. For Krzysztof Wicher at Macomics Limited, that meant finding a way to get high-quality antibodies quickly and more affordably than production in-house.

Why Biointron Won the Job

Macomics compared several CROs, but Biointron stood out - not because of one single thing, but because everything worked together.

• Faster than anyone else - even with international shipping from China, Biointron outpaced competitors, including those with European facilities

• Pricing that fit the budget - essential for a discovery-stage biotech

• Comprehensive quotations - including antibody design, sequences, and modifications

• Direct scientist-to-scientist contact - fast, clear communication

• Helpful troubleshooting - Biointron scientists always offered advice

“Ordering was very easy,” says Krzysztof. “We just sent the sequences, and Biointron’s scientists did the rest. They were faster and cheaper than other CROs we’ve used, and their communication was excellent.”

The Results

Over a four-year partnership, Biointron produced hundreds of antibodies and proteins for Macomics - primarily IgG4s and IgG1s from human and mouse origins with some rabbit scaffolds, along with Fc fusions, Fabs, and recombinant proteins.

The impact was clear:

• Projects moved faster than with other CROs or in-house production

• Internal scientists could focus on functional testing and downstream assay development

• Macomics avoided significant capital expenditure on equipment and staff

• Nearly all antibodies bound to their intended targets (those that didn't were attributed to a different CRO’s earlier assays)

Dedicated People, Caring Partners

At Biointron, every project gets a dedicated scientist/project manager - someone who knows the details, follows the progress closely, and is there to answer questions quickly.

We don’t just make antibodies; we care about the science and the people behind it. We treat each customer’s work as if it were our own, because your breakthroughs matter to us.

A Specialist, Not a Generalist

For Macomics, the decision to stick with Biointron over four years came down to trust - in both the speed and the science.

Krzysztof recommended Biointron to many other biotech colleagues in the UK, confident they’d have the same experience.

At Biointron, we don’t try to do everything. We’re not generalists.
We’re specialists — and our specialty is antibodies. From sequence to shipment, we focus entirely on designing, optimizing, and producing antibodies that power discovery.

Antibody production