Antibody-based diagnostics are tests that utilize antibodies to detect specific molecules that are indicative of a particular disease or condition. These diagnostic tools leverage the high specificity of antibodies, and the ability to produce large quantities of them. For example, monoclonal antibodies (mAbs) can be developed to recognize unique antigenic determinants on specific pathogens associated with a disease.

A common theme emerging from recent antibody research is the development and validation of advanced diagnostic tools based on antibody detection. Multiple studies highlight the creation of novel biosensors and assays designed to enhance the sensitivity, specificity, and efficiency of detecting antibodies across various diseases.

Discover the applications of antibodies in research, diagnostics, & therapeutics. Learn the differences between polyclonal, monoclonal, & recombinant antibodies.

VHH antibodies, also known as nanobodies, are single-domain antibodies that are derived from camelid heavy-chain antibodies. Due to their small size (~ 15 kDa) and diverse applications in bio-derived therapeutics, these antibodies have widespread attention in the research and development community, with some examples below from just this week!

Explore antibody-based diagnostics, including ELISA, Western blot & immunofluorescence, for detecting pathogens & biomarkers. Learn how these techniques improve accuracy!

Understand antibody specificity & selectivity for precision in research. Learn how to enhance assay accuracy by selecting antibodies with high target recognition & minimal cross-reactivity.

Discover antibody functions, classes, and innovations, from monoclonal therapies to diagnostic applications. Learn about immune memory, B cells, and antibody engineering.

Learn about Western blotting, a key technique for protein analysis, antibody validation & disease diagnostics. Discover its applications in research & clinical settings!

Discover how antibodies enable research into protein-protein interactions through immunofluorescence, immunoprecipitation, & co-immunoprecipitation methods.

Explore antibody stability challenges in biologics development & solutions like protease minimization, CDR grafting & optimized storage to enhance efficacy & safety.