Several factors can affect an antibody’s stability, including protein structure and concentration, temperature, interfaces, light exposure, contaminants, and agitation. This is of particular importance when developing antibody therapeutics for their immunogenicity potential. The instabilities may be either chemical, physical, or a combination of both.

Explore antibody stability challenges in biologics development & solutions like protease minimization, CDR grafting & optimized storage to enhance efficacy & safety.