T cells, also known as T lymphocytes, originate from stem cells in the bone marrow but mature in the thymus. These cells are essential in adaptive immunity, providing targeted responses to pathogens and abnormal cells, including cancer cells. Their ability to differentiate into diverse functional subsets makes them pivotal for maintaining immune balance, eliminating threats, and contributing to therapeutic strategies like immunotherapy.

Explore the role of TCR-like antibodies in targeting peptide-MHC complexes for precise cancer treatment, including development techniques and therapeutic applications.

Antibody drugs for diabetes typically target specific molecules involved in the regulation of blood sugar levels or the immune response against insulin-producing cells, or specific hormones or receptors involved in glucose metabolism. For instance, teplizumab (Tzield), targets CD3 on T cells, thus deactivating immune cells which attack β-cells.