Citations Database | Biointron

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Antibody or Protein Production Catalog Products Antibody Discovery Hybridoma Sequencing

Journal

Acta Pharmaceutica Sinica B Advanced Healthcare Materials Antibodies Antibody Therapeutics Biosensors Cancer Immunology Research Cancer Letters Cancer Research Communications Cancers Carbohydrate Polymers Cell Biomaterials Cell Death and Disease Cell Research Cell Systems EMBO Molecular Medicine eBioMedicine European Journal of Immunology Food and Agricultural Immunology Frontiers in Immunology iScience Immunopharmacology and Immunotoxicology Immunotherapy JCI Insight Journal for ImmunoTherapy of Cancer Journal of Autoimmunity Journal of Bone and Mineral Research Journal of Healthcare Engineering Journal of Immunological Methods Journal of Immunotherapy Journal of Virology MAbs Molecular Cancer Therapeutics Molecular Metabolism Nature Chemical Biology Nature Communications Neurotoxicity Research npj Vaccines Oncogene Research Science Advances Science China Life Sciences Science Immunology Scientific Reports Small Viruses

A Novel Designed Anti–PD-L1/OX40 Bispecific Antibody Augments Both Peripheral and Tumor-Associated Immune Responses for Boosting Antitumor Immunity

Authors: Baocun Li, Shiyong Gong, Nianying Zhang, Beilei Shi, Zhou Lv, Yu Zhang, Naren Gaowa, Liqin Dong, Danqing Wu, Jianfu Wu, Fan Liu, Rui Zhang, Ramin Behzadigohar, Vinod Ganju, Chengbin Wu, Xuan Wu

Journal: Mol Cancer Ther 2024

PubMed ID: 39575565

DOI: https://doi.org/10.1158/1535-7163.MCT-24-0330

Products & Services: OX40 ECD wild-type (WT) and four mouse OX40 chimeras (each hOX40 CRD was replaced with its hOX40 counterpart) were expressed and purified by Biointron through transfection

Nov 18, 2024

Insights into the mechanisms of serplulimab: a distinctive anti-PD-1 monoclonal antibody, in combination with a TIGIT or LAG3 inhibitor in preclinical tumor immunotherapy studies

Authors: Yizhou Zhang,Ruicheng Wei,Ge Song,Xinyi Yang,Mengli Zhang,Wei Liu,Aiying Xiong,Xuehan Zhang,Qianhao Li,Wan-Jen Yang,Chencheng Han,Rui Liu,Chen Hu,Qingyu Wang,Jun Zhu & Yongqiang Shan

Journal: Mabs

PubMed ID: 39497266

DOI: https://doi.org/10.1080/19420862.2024.2419838

Products & Services: B2014, B6924

Nov 04, 2024

Selective targeting of oncogenic hotspot mutations of the HER2 extracellular domain

Authors: Injin Bang, Takamitsu Hattori, Nadia Leloup, Alexis Corrado, Atekana Nyamaa, Akiko Koide, Ken Geles, Elizabeth Buck & Shohei Koide

Journal: Nature Chemical Biology

PubMed ID: 39438724

DOI: https://doi.org/10.1038/s41589-024-01751-w

Products & Services: The production of sTL18/UCHT1 scDb-Fc was done by Biointron using 200 ml of CHO cells.

Oct 22, 2024

Serum ECM1 is a promising biomarker for staging and monitoring fibrosis in patients with chronic hepatitis B

Authors: Lian Liu, Danyan Zhang, Rong Fan, Shipeng Cheng, Jichao Yang, Liyan Ma, Zhiyang Ling, Yaguang Zhang, Jinlin Hou, Xiaomei Wang, Bing Sun & Junqi Niu

Journal: Science China Life Sciences

PubMed ID: 39348048

DOI: https://doi.org/10.1007/s11427-024-2691-0

Products & Services: The ECM1 coding-region templates were synthesized by Biointron, codon-optimised for transcription/ translation in human cells and subcloned into the mammalian expression vector

Sep 27, 2024

Pretrainable geometric graph neural network for antibody affinity maturation

Authors: Huiyu Cai, Zuobai Zhang, Mingkai Wang, Bozitao Zhong, Quanxiao Li, Yuxuan Zhong, Yanling Wu, Tianlei Ying & Jian Tang

Journal: Nature Communications

PubMed ID: 39242604

DOI: https://doi.org/10.1038/s41467-024-51563-8

Products & Services: All antibodies were produced by Biointron Biological Inc

Sep 06, 2024

A pan-allelic human SIRPα-blocking antibody, ES004-B5, promotes tumor killing by enhancing macrophage phagocytosis and subsequently inducing an effective T-cell response

Authors: Xiaofeng Niu, Chunnian Wang, Haixia Jiang, Rui Gao, Yefeng Lu, Xiaoli Guo, Hongping Zhou, Xue Cui, Jun Sun, Quan Qiu, Dawei Sun, Hongtao Lu

Journal: Antibody Therapeutics

PubMed ID: 39257438

DOI: https://doi.org/10.1093/abt/tbae022

Products & Services: Two human IgG4 anti-SIRPα reference antibodies, HEFLB and hu1H9, were produced at Biointron according to patents WO 2017/178653 A2 and WO 2019/023347 Al. Anti-PD-L1 single-domain antibody KN035 was produced at Biointron according to patent CN 111116747 A (SEQ ID NO: 33). Anti-SIRPγ antibody LSB2.20 was purchased from Biolegend. Human IgG1, human IgG4, and mouse IgG1 isotype control antibodies were all purchased from Biointron as were the following recombinant proteins: mouse Fc-tagged huCD47 ECD, mouse Fc-tagged huSIRPα V1 ECD, and 6 × His tagged huSIRPα V8 ECD.

Aug 28, 2024

Genetic barrier to resistance: a critical parameter for efficacy of neutralizing monoclonal antibodies against SARS-CoV-2 in a nonhuman primate model

Authors: Christiane Stahl-Hennig, Antonia Sophia Peter, Arne Cordsmeier, Nicole Stolte-Leeb, Ramona Vestweber, Eileen Socher, Samuel Alberto Merida, Ulrike Sauermann, Martina Bleyer, Kirsten Fraedrich, Thomas Grunwald, Thomas H. Winkler, Armin Ensser, Hans-Martin Jäck, Klaus Überla

Journal: Journal of Virology

PubMed ID: 38899895

DOI: https://doi.org/10.1128/jvi.00628-24

Products & Services: TRES6 and 4C12 were produced in CHO cells and purified by affinity chromatography (Biointron)

Jun 20, 2024

C1q enables influenza hemagglutinin stem binding antibodies to block viral attachment and broadens the antibody escape repertoire

Authors: Ivan Kosik, Jefferson Da Silva Santos, Matthew Angel, Zhe Hu, Jaroslav Holly, James S. Gibbs, Tanner Gill, Martina Kosikova, Tiansheng Li, William Bakhache, Patrick T. Dolan, Hang Xie, Sarah F. Andrews, Rebecca A. Gillespie, Masaru Kanekiyo, Adrian B. McDermott, Theodore C. Pierson, Jonathan W. Yewdell

Journal: Science Immunology

PubMed ID: 38517951

DOI: https://doi.org/10.1126/sciimmunol.adj9534

Products & Services: Custom produced SARS2 Spike human IgG1 monoclonal RBD Abs and nonRBD Abs based on available VH, VL sequences (Biointron)

Mar 22, 2024

Colorectal cancer cells secreting DKK4 transform fibroblasts to promote tumour metastasis

Authors: Xue Li, Yulin Chen, Ran Lu, Min Hu, Lei Gu, Qiaorong Huang, Wentong Meng, Hongyan Zhu, Chuanwen Fan, Zongguang Zhou & Xianming Mo

Journal: Oncogene

PubMed ID: 38519641

DOI: https://doi.org/10.1038/s41388-024-03008-1

Products & Services: Human recombinant DKK4 protein (BIOINTRON, customized product, 20 μg/kg)

Mar 22, 2024

The spatial and single-cell analysis reveals remodeled immune microenvironment induced by synthetic oncolytic adenovirus treatment

Authors: Gan Liu, Qifan Hu, Shuguang Peng, Hui Ning, Jiajia Mai, Xi Chen, Minzhen Tao, Qiang Liu, Huiya Huang, Yun Jiang, Yanhua Ding, Xuegong Zhang, Jin Gu, Zhen Xie

Journal: Cancer Letters

PubMed ID: 38008394

DOI: https://doi.org/10.1016/j.canlet.2023.216485

Products & Services: Mouse PD-L1 antibody was bought from Biointron Biotechnology (B176401)

Jan 28, 2024