Ozempic, a brand name for the drug semaglutide, was originally developed to manage type 2 diabetes by improving blood sugar control. As a GLP-1 receptor agonist, it mimics a hormone that regulates glucose metabolism and appetite. Beyond its success in diabetes treatment, Ozempic has garnered signifi

Explore the role of TCR-like antibodies in targeting peptide-MHC complexes for precise cancer treatment, including development techniques and therapeutic applications.

ADCs for ES-SCLC. Image credit: DOI: 10.3390/genes15060701Extensive-stage small-cell lung cancer (ES-SCLC) is a particularly aggressive form of lung cancer characterized by rapid growth and early metastasis. Antibody drugs, especially immune checkpoint inhibitors, have emerged as a promising treatme

Discover cancer immunotherapy techniques like monoclonal antibodies, checkpoint inhibitors, & ADCs. Learn how targeted delivery & tumor selectivity improve cancer treatment.

Explore how vaccines stimulate antibody production, the mechanisms behind immune responses, and factors influencing vaccine efficacy for long-term immunity.

Image credit: DOI: 10.1038/s41577-021-00542-xThe progress of COVID-19 therapies has seen remarkable strides, particularly in the development and application of antibody-based treatments. Early in the pandemic, the focus was on supportive care, but the rapid advancement in antibody therapies has sign

Examine how antibody discovery drives CAR-T cell engineering, enhancing specificity, reducing toxicity, and advancing next-generation cancer immunotherapies.

Discover the history of Muronomab (Orthoclone OKT3), the first monoclonal antibody approved by the FDA for preventing transplant rejection & its impact on immunology.

Highlights from Biointron’s Lunch & Learn with MassBio: HTP antibody platforms, alpaca VHH discovery, bispecific antibodies, & ADC development advancements.

DOI:10.1126/science.adg0564 B cells, or B lymphocytes, are a crucial component of the adaptive immune system andhumoral immunity. They originate from the bone marrow and mature in secondary lymphoid organs, such as the spleen and lymph nodes. The B ce

Discover the evolution of engineered antibody formats from monoclonal to bispecific antibodies, highlighting milestones in immunotherapy and clinical applications.

Learn how antibodies neutralize pathogens, aid in vaccine development, & enhance immune responses through opsonization. Explore their vital role in human health.

Explore the role of anti-idiotype antibodies & critical reagents in therapeutic antibody development, ensuring specificity, potency & safety in drug testing

Explore ADCs in antibody research, combining monoclonal antibodies with cytotoxic drugs for precise cancer targeting. Learn their history, design, and benefits.

Here at the AACR Annual Meeting 2024, there are over 7000 abstracts, 300 poster presentations, and 50 symposia all about cancer research. A few topics that are currently trending in the conference include cancer vaccines, AI for diagnostics, novel immunotherapies, and antibody-drug conjugates (ADCs) as a new modality.